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Her focus is on accuracy and fidelity to current published research, with all content presented for laboratory research use only

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5-Amino-1MQ is a substrate-mimetic inhibitor that occupies the nicotinamide binding site, with a reported IC of 1.2 0.1 M (Neelakantan et al., J Med Chem, 2017)

Yi D, Kamei CLA, Cools T, Vanderauwera S, Takahashi N, Okushima Y, Eekhout T, Yoshiyama KO, Larkin J, Van den Daele H et al (2014) The Arabidopsis siamese-related cyclin-dependent kinase inhibitors SMR5 and SMR7 regulate the DNA damage checkpoint in response to reactive oxygen species

By reducing the volume of blood pooling in the legs, Pycnogenol can help to lower the compensatory rapid heart rate (tachycardia) that POTS patients experience upon standing, thereby improving orthostatic tolerance and reducing episodes of dizziness and pre-syncope