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Blood pressure and lipid profiles may also change
Expert Opinion on Drug Safety , 18
Sample sizes between 30 and 36 participants were noted for the three exit interview studies where data were available, comprising 4%, 6%, and 26% of the trial population for Ryeqo, Opzelura, and Xermelo, respectively (Table 3)
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Additional important safety considerations include: Risk of hypoglycaemia when combined with insulin or sulfonylureas Potential for dehydration and acute kidney injury from severe gastrointestinal symptoms Increased risk of diabetic retinopathy complications with rapid glucose lowering, particularly with semaglutide Importantly, memory loss or cognitive impairment is not listed among the recognised adverse effects in the Summary of Product Characteristics (SmPC) for any GLP-1 receptor agonist licensed in the UK
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