In contrast to HmbR, which preferentially but not exclusively recognizes human hemoglobin, TbpA/TbpB and LbpA/LbpB recognize exclusively human transferrin and lactoferrin, respectively, and this selectivity strongly contributes to the narrow host spectrum of the meningococcus (Perkins-Balding et al., 2004)
2.3 Experimental protocol Following 1 week of acclimation, six rats were allocated randomly to one of four groups: Rats in Group 1, the control group, were given saline intraperitoneally (IP) twice weekly for 6 weeks
For researchers with pre-existing cardiovascular conditions, cardiac medications, or other risk factors, the heart rate increase warrants closer monitoring and slower dose escalation
Plaintiffs must also demonstrate that the drug manufacturer failed to warn about these risks
The FDA medications are extremely expensive