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As NAD+ declines, skin becomes thinner, drier, and more prone to wrinkles and damage
Data availability Additional supporting data the findings of the study are available from the lead contact, Sang-Ku Yoo ([email protected]), upon reasonable request
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This initial recognition step allows the peptides N-terminus to engage deep within the receptor TMD core, triggering a conformational change proximal to the intracellular region that results in G protein coupling and activation of the downstream signalling cascade 3,4,5,6,7
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