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it is the product of one of the most metabolically active processes in the human body

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Inhibition of Glutamate cysteine ligase depletes neuronal glutathione, elevates glutamate and increases excitatory neurotransmission Glutamate cysteine ligase (GCL) is the rate limiting step for glutathione synthesis, and utilizes glutamate as a substrate

Greco M, Brugnara M, Zaffanello M, Taranta A, Pastore A, Emma F (2010) Long-term outcome of nephropathic cystinosis: a 20-year single-center experience

We performed subgroup analyses to determine if the treatment effect of L-C on TPV or maximum area stenosis differed by red meat consumption, baseline stenosis, baseline TPV, recruitment site, sex, or eGFR