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Heavy metals are introduced into our body either directly through the air we inhale, or indirectly through the soil, plants and animals

Supports interpretation of reactive metabolite screening data and structure-risk discussions

In many scenarios, activation of NRF2 has been reported to be a stress response that is required to prevent the accumulation of oxidative stress and subsequent tissue damage

It inhibits NNMT (nicotinamide N-methyltransferase), an enzyme regulating metabolism, fat storage, and NAD+ consumption.[4][27][6] NNMT methylates nicotinamide, a NAD+ breakdown product, diverting it from recycling and reducing available NAD+

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