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Always discuss with your healthcare provider about timing and protective measures to avoid adverse effects from this combination
Our clinicians prefer to classify these medications as incretin mimetics, which include drugs that act as GLP-1s, GLP-1/GIPs, and others
Synthetic small molecules allow selective targeting but face challenges, including limited efficacy, extrahepatic toxicity, and narrow therapeutic windows
Hormetic Response Mechanisms Hormesis describes the biological phenomenon where low doses of a stressor produce beneficial adaptive responses while higher doses become harmful
Further data on the effects of tirzepatide on cardiovascular risk will be elucidated in the phase 3 SURPASS-CVOT trials [9]
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