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Lancet Diabetes Endocrinol 12(9):631642 Jastreboff AM, le Roux CW, Stefanski A, Aronne LJ, Halpern B, Wharton S, Wilding JPH, Perreault L, Zhang S, Battula R, Bunck MC, Ahmad NN, Jouravskaya I, SURMOUNT-1 Investigators (2025) Tirzepatide for obesity treatment and diabetes prevention
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doi:10.1111/acel.12368
Results: L-TMEM41B single KO mice had massive hepatic steatosis by 1 month with a decrease in VLDL secretion
It works by suppressing appetite, helping people feel full sooner so they eat less throughout the day
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