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Weight Loss Efficacy: Head-to-Head Trial Data Retatrutide produced the highest average weight loss in its Phase 2 trial, but the two drugs were tested in separate studies at different time points, so the comparison is indirect rather than a direct trial

doi: 10.1016/j.molmet.2022.101533 38 PetersenJLudwigMQJuozaityteVRanea-RoblesPSvendsenCHwangEet al

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FDA Approval Timeline: Step by Step This timeline assumes no unexpected safety signals emerge and reflects a roughly 3-month delay compared to the previous NDA-based estimate, driven by the shift to a Q1 2027 BLA filing