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GHK-Cu has a strong safety profile in topical use
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after 12pm ships next business day What is DSIP (Delta Sleep-Inducing Peptide)
It acts pro-angiogenically via VEGFR2: the peptide promotes VEGFR2 internalization and activates the VEGFR2-Akt-eNOS pathway, which is blocked by the endocytosis inhibitor Dynasore, and in preclinical models it increased vessel density as well as the restoration of blood flow in the ischemic rat hindlimb Hsieh et al., 2017
Radioligand and fluorescent binding assays, competition binding, recombinant receptor-expressing cell lines, functional readouts through a defined coupling pathway, and antagonist controls demonstrating that an effect is receptor-mediated
