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I was curious to try GLP medications for my RA and joint pain, but I have a history of eating disorder, so my doctor didnt think it was appropriate for me. Heidi, 47 years old, diagnosed with RA, mixed connective tissue disease, and lupus My rheumatology team considered adding a GLP medication, but I have dysmotility and malabsorption from autoimmune disease, so it was not a good fit for me. Elaine, 48 years old, living with RA and scleroderma Some people expressed interest in knowing more about GLP-1s for RA

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By competitively binding FOXO4, it prevents FOXO4 from sequestering p53, thereby restoring the cells intrinsic apoptotic signaling capacity

BPC-157 is described as well tolerated and without demonstrated toxicity in rodents, but the human safety dossier is unpublished, and over 80 percent of the literature comes from a single research group, so independent replication is limited Sikiric et al., 2025

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