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3- Safety: Trials 7 reported no serious adverse events at the studied ranges

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Additional benefits observed: Substantial reduction in knee osteoarthritis pain (75.8% reduction in pain scores) Improved cardiovascular risk markers (non-HDL cholesterol, triglycerides, blood pressure) Up to 86% of participants with fatty liver disease achieved normal liver fat levels Early research suggests retatrutide may lead to substantial weight loss in clinical trial settings, but long-term safety, tolerability, and real-world outcomes still need more data

The generational breakdown of respondents was as follows: Gen Z (13%), millennials (42%), Gen X (34%), and baby boomers (11%)

Researchers published this finding On March 6, 2024 in JAMA Surgery