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Adverse effects such as tachycardia, infections, headaches, dizziness, nausea, vomiting, diarrhea, and dyspepsia, as well as contraindications such as a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2, hypersensitivity, severe gastrointestinal diseases, renal impairment, and pregnancy have been noted
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GLP-1 agonists should not directly impair sleep, but if you are taking doses late in the day, residual GI discomfort may disrupt rest
However, ongoing monitoring depends on patient-initiated check-ins rather than mandatory follow-up labs
Q1 2027: Lilly plans to submit its BLA to the FDA
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