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No FDA status Not FDA-approved Compound Semaglutide Mechanism GLP-1 receptor agonist
Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent
They might be given every 1-3 months, depending on how the patient is doing and their ongoing needs
The right protocol depends on factors like your baseline metabolic health, body composition, and other therapies you might be using
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