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The discrepancy between our robust finding of reduced thalamic GSH and the less consistent findings in the occipital cortex raises important questions about regional specificity

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Reported adverse events primarily reflect dose-dependent or infusion-related effects and include: Mild to moderate gastrointestinal , including diarrhea, nausea, heartburn, abdominal discomfort.3,57,1718 Odiferous urine , a benign and transient observation.17 Headache, dizziness, or fatigue 3,67,18 Cutaneous reactions , including rash, pruritus, or urticaria.3,67,1718 Transient hypoglycemic episodes , most commonly reported in individuals with diabetes.7,18 Hepatic effects , including transient elevations in liver enzymes in clinical studies and, at excessively high doses in nonclinical studies, evidence of acute hepatic injury.4 Systemic allergic reactions , including rare reports of anaphylaxis.6,1718 Cardiovascular symptoms , such as palpitations, tachycardia, and, very rarely, arrhythmias.56,10,18 Insulin autoimmune syndrome , a rare immune-mediated hypoglycemia.1617 Reported adverse events should be interpreted within the context of study design, population, dose, and duration, and should prompt evaluation of dosing, infusion rate, and concomitant medications as appropriate

For further reading, refer to National Institutes of Health (NIH)