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For those with low strength, further assessment of muscle mass (such as bioelectrical impedance analysis and dual-energy X-ray absorptiometry) is conducted, and the severity is defined by physical manifestations (such as walking speed and the Brief Physical Condition Scale) [2, 3]

A Phase 2 trial by Metabolic Pharmaceuticals found that while the compound was well-tolerated, it did not produce statistically significant weight loss versus placebo at the doses tested

Like Januvia, it's also used for managing blood sugar levels in adult patients with type 2 diabetes

doi:10.3390/ijms19071987 5

Although it is not yet available, the manufacturer, Novo Nordisk, filed for FDA approval in December 2025, with FDA review expected in 2026