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Loss or mutation of p53 disrupts these pathways, promoting cellular immortalisation, checkpoint defects, and genomic instability, which allows replication of damaged DNA and contributes to tumourigenesis (35, 36)
Special considerations : The FDA prescribing information for tirzepatide notes that it may decrease exposure to oral contraceptives, particularly during dose initiation and escalation
Apply your next regularly scheduled dose
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Ongoing research and real-world evidence continue to enhance our understanding of semaglutides safety and help ensure that patients receive the best possible care
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