These inflammatory mediators affect hypothalamic-pituitary-ovarian axis signals and can modify cycle timing, LH surge precision, and follicular development
Additionally, in a 30-day placebo-controlled trial in 300 adults (aged 18-65 years), supplementation with the B vitamins (at doses of about 3 to 13 times the RDA, excluding folic acid), vitamin C (1,000 mg/day), calcium (100 mg/day), and magnesium (100 mg/day) was associated with significant improvements in various scores of psychological stress compared to a placebo (139)
Learn everything you need to know about B12 injections below, including how they work and their benefits over cortisone
Among those on the highest dose, 54.6% achieved at least 10% weight loss, 36.0% achieved 15% or more, and 18.4% achieved 20% or more
Lancet (2021) 398:58398