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Putting the trial numbers into perspective Historically, anti-obesity drugs produced average weight losses in the single digits (510%), and even the best options rarely approached double-digit percentages at the population level
The immunoprecipitates were washed four times with IP buffer
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Compare this to 1820 percent over 72 weeks for tirzepatide, or 14.9 percent over 68 weeks with semaglutide (both in phase III trials)
Cochrane Database Syst Rev (2015) 10:CD005328
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