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Either way, the practical implication is similar, and it is arguably the most consequential consideration for anyone planning future work: on the brain-access hypothesis, novel dual GLP-1/GIP agonists engineered specifically for brain entry would be more rational next candidates to test than repurposed diabetes drugs chosen for market availability
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Their study concluded that this is evidence that when GLP-1 was added to isolated human islets it was found that it inhibits cell apoptosis
It would be great to see more studies that take genes into account
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