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Where semaglutide showed benefit was across a range of secondary and exploratory outcomes during the last 4 weeks of treatment: Drinks per drinking day (consumption counted only on days participants actually drank) decreased significantly Naturalistic craving, measured with the Penn Alcohol Craving Scale, decreased significantly Alcohol-related negative consequences, measured with a PROMIS alcohol measure, decreased at a significantly greater rate than with placebo Among the subset of participants who used cannabis at baseline, semaglutide significantly reduced cannabis use days over the treatment period Semaglutide-treated participants were also significantly more likely than those on placebo to drop their World Health Organization risk drinking level by a full category or more over the treatment period
The implications cascade through multiple metabolic pathways
Inside the Wine, Tea, and Chocolate Debate Insulin, he adds, is still rarely tested
The two most popular weight loss drugssemaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro/Zepbound)target GLP-1 alone or GLP-1 plus GIP, but not glucagon
Treatment may also include other healthcare components, including dietitian support and coordination with other medical professionals
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