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Abnormal exocytotic release of glutamate in a mouse model of amyotrophic lateral sclerosis
To put that in perspective: if your therapeutic dose is 500 mcg, you'd theoretically need 500,000 mcg (500 mg) to approach potentially toxic levels
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How do you fix frown lines on your forehead
Same here: there is meaningful, sometimes dramatic change, but it is contingent on continued use
Compared to constructs without IGF-1 overexpression, IGF-1-overexpressing constructs significantly promoted osteochondral repair and reduced cartilage degeneration near the defect
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