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The existing evidence base consists primarily of preclinical studies, small observational reports, and theoretical mechanisms rather than large-scale randomised controlled trials
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Around 10% of the patients withdrew treatment due to GI adverse events
Adult Results and Side Effects Amelia Caretto presents the results for the five adult patients, noting a decrease in BMI and improved HbA1c in four patients
Some people respond extremely well, while others lose only a modest amount or discontinue treatment because of side effects, costs, insurance problems, or personal preferences
