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This has not been studied systematically, but the pharmacological principle of dose-response suggests that higher doses may produce more pronounced neurochemical effects, including effects on the reward system
Pure Lab Peptides Tirzepatide (10 mg) product page with quality documentation and batch COAs
*In a 72-week study of adults without diabetes (SURMOUNT-1), average weight loss was 15.0% (34 lbs) for 5mg, 19.5% (44 lbs) for 10mg, 20.9% (48 lbs) for 15mg, and 3.1% (7 lbs) for placebo
Current research limitations include a small number of NAION cases among over 17,000 patients in the study, mainly white participants, and uncertainty regarding medication adherence
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