REDEFINE 2 (obesity with type 2 diabetes) A phase 3a, 68-week, double-blind, placebo-controlled trial across 12 countries (NCT05394519 [11] ) in 1,206 adults with BMI 27, HbA 1c 710%, and type 2 diabetes, randomised 3:1 to CagriSema 2.4/2.4 mg (n=904) or placebo (n=302)
This comprehensive approach ensures that researchers can tailor liposomal formulations to specific therapeutic needs, achieving maximum stability, reproducibility, and performance in preclinical studies
This is called muscle guarding
The standard laboratory workflow is to wipe the rubber stopper of both the BAC water vial and the lyophilised peptide vial with an alcohol swab, withdraw the chosen volume of BAC water with a sterile syringe, and inject it slowly down the inside wall of the lyophilised vial without disturbing the peptide cake
Clean both vial stoppers with alcohol swabs