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Who should (and should not) take semaglutide for weight loss
Impact evaluation: JCEMs 2024 Journal Impact Factor is approximately 4.7 (CiteScore 9.1), therefore this is a Medium-impact journal Related Reading: Canagliflozin - Another Top Longevity Drug Canagliflozin for Anti-aging (part 2) SGLT2 Inhibitor Canagliflozin eliminates senescent cells and alleviates pathological aging (in mice) ARPA-H puts $144 million into healthspan-focused human trials (mTOR inhibitor, SGLT2) 14 Likes Empagliflozin: The Diabetes Pill That Might Also Keep Old Kidneys Young DeStrider July 11, 2026, 3:52am #2 Yet another excellent reason to use SGLT2Is
GLP-1s like semaglutide (Ozempic, Wegovy) , dulaglutide (Trulicity) , and liraglutide (Victoza, Saxenda) are responsible for a handful of mechanisms that aid in controlling high blood sugar
Tirzepatide as an alternative If semaglutide is not working for you or the regulatory landscape concerns you, tirzepatide is a dual GIP/GLP-1 receptor agonist that has shown even greater weight loss in clinical trials
Earlier research into GLP-1 receptor agonists and substance use drew on smaller studies and animal models
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