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Although Se could be a viable option to increase GPx activity in individuals with high oxidative stress, Se supplementation may be most effective in combination with another therapeutic known to directly increase GSH

Some clinical trials have been conducted on the repurposing of pioglitazone for PD treatment

And GLP-1 can inhibite hepatocyte apoptosis which induced by NLRP3 through autophagy in mitochondria, weakening the intrahepatic inflammatory response, thereby inhibiting the transition from simple fatty liver to nonalcoholic steatohepatitis (NASH)

Other plant-based extracts have also been linked to weight loss or gut health