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This situation plays a significant role in the pathogenesis of liver diseases, especially cirrhosis and fatty liver disease (Arroyave-Ospina et al

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The gentle ramp from 0.25 mg up to 2.4 mg mirrors the phase 2 dose-finding schedule that achieved meaningful weight loss while keeping nausea and other gastrointestinal effects manageable [1] [4]

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Biomaterials 31:76317639

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