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In a Phase 2 trial that was published in the The New England Journal of Medicine participants achieved up to 24.2% average body weight loss at 48 week s while some higher dose groups gained 17.5% weight loss within just 24 weeks
The localized high concentration of CPPs may influence the integrity of tight junctions, subsequently affecting the transduction of cargos through the paracellular cleft (Kristensen and Nielsen, 2016)
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357 (2002), accessed December 19, 2025, THOMPSON V
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