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These metabolites, obtained by the activity of the microbial populations in the intestine, contribute to the health maintenance by crossing the BBB to exert antiinflammatory, antioxidant, and cognitive effects, which can help to mitigate the AD main hallmarks such as A aggregation, neuroinflammation, and synaptic loss [21, 24]

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Vero cells were treated with different concentrations of compounds with DMSO as control and incubated in the presence of 5% CO 2 at 37 C for 24 h

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