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doi:10.1001/jamaophthalmol.2024.2296 Lisco G, De Tullio A, Disoteo O, et al
The Study Gap Clinical trials focus on physical outcomesweight loss, blood sugar levels
Both are valid
The pharmacokinetics of LY3437943 (retatrutide) support once-weekly administration due to an elimination half-life of approximately 6 days. Jastreboff AM et al., Nature Medicine, 2023 This extended half-life is made possible by attaching a fatty acid chain to the peptide, allowing it to bind to albumin a common protein in your blood that acts like a slow-release carrier
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