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However, another randomized, double-blind, placebo-controlled trial in 181 patients with diabetic neuropathy found that oral supplementation with either 600 mg/day, 1,200 mg/day, or 1,800 mg/day of lipoic acid for five weeks significantly improved neuropathic symptoms (77)

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Dosing Phases, Titration & Cycling The documented GLOW research schedule is a three-phase frequency taper rather than a dose-size titration

These results show that BSO treatment modulates the levels of the transcripts encoding AA transporters related to L-cys/L-cys 2 availability in the striatum

This indicates that while DSIP may have a tendency to reduce infarct size, the effect was not robust enough to be considered statistically significant under the experimental conditions