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(NOTE: There is an ongoing debate about whether 5-Amino 1MQ should be classified as a small molecule or a peptide, but thats a discussion far beyond the scope of this article) It was discovered in 2017 by researchers at the University of Texas who were attempting to discover small, selective, and membrane-permeable inhibitors of an enzyme called nicotinamide N -methyltransferase (NNMT)

For powder handling, researchers should minimize dust generation, avoid skin and eye contact, avoid inhalation, and use appropriate containment and personal protective equipment according to the institutions chemical hygiene plan

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