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Double-blind parallel design pilot study of acetyl levocarnitine in patients with Alzheimer's Disease
This is made easier by the surface glycocalyx, intercellular junctions, and the basement membrane working together
Biotechnol Adv
The best approach: do nothing
They show some positive effects on sleep quality, such as restful sleep, but they dont show that melatonin supplements reverse the cognitive deficits of AD.[ref] One placebo-controlled trial of six months of 2mg time-release melatonin in people with mild to moderate AD did show positive results on cognitive performance compared to placebo
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