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A 2026 systematic review and meta-analysis of controlled human trials found that allulose (and its cousin tagatose) meaningfully reduced the postprandial glucose response when used in place of added sugars, an effect that may be especially useful in the window right after a carbohydrate-rich meal

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Arifin WN, Zahiruddin WM

Preliminary study featured the continuous subcutaneous infusion of GLP-1 over a duration of six weeks showed an effective decreases in fasting and postprandial glucose levels, as well as involved enhancements in A1C, improvement in insulin sensitivity and body weight (Zander et al