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SAG : Oral SAG significantly raises plasma GSH levels compared to plain GSH, but intact SAG is nearly undetectable in plasma (rapid conversion)
Higher doses reached that plateau later in the trial. In a 112-week step-down trial, participants maintained 21.9% loss on the top dose, 16.6% after stepping down to 5 mg, and 9.9% on placebo
In contrast, aged animals exhibited no significant changes in macrophage cytokine levels, suggesting that Epitalons therapeutic value may lie more in correcting age-related immune deficits than in stimulating already functional systems
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