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They are not FDA approved, and we typically do not recommend them," she said
A recent large-scale clinical trial has confirmed that tirzepatide, a dual GIP and GLP-1RAs, resulted in a weight loss of up to 20.9% in adults with body fat mass of 30 or more after 72-week follow-up [22]
An important note: Zepbound has been approved for sleep apnea and Wegovy for cardiovascular risk, with weight loss as a side benefit
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Inositol metabolic signals, mainly in PCOS Myo-inositol can improve insulin sensitivity and some metabolic markers in PCOS, but a 20232024 systematic review for the international PCOS guidelines called the evidence limited and inconclusive, and weight/waist measures often did not improve
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