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Description

In both mouse and human beta cells, the ability of GLP-1 to induce membrane depolarisation and initiate action potential firing depend on extracellular Na + and TRPM5 activity [23, 29, 30]

10.1016/j.ijpharm.2018.01.006 69 RaghavanS

Investigators are studying whether the combined triple-agonist effect on appetite, energy expenditure, and hepatic lipid handling translates to reductions in liver fat content