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Dr Khan added that following a Mediterranean diet will lead to improved insulin sensitivity compared to diets high in saturated fats.
This lack of efficacy may be attributed to the low plasma and sputum concentrations of NTZ and the high plasma protein binding of tizoxanide, the active metabolite of NTZ [80], highlighting the need for further pharmacokinetic optimization and clinical research to better understand its potential role in TB treatment
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Injectable vitamin B12 avoids this limitation by: Delivering a concentrated dose directly into systemic circulation Ensuring near-complete absorption Rapidly increasing serum B12 levels Because of this mechanism, B12 shots are often recommended for moderate to severe deficiencies or when quick correction is required
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