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Body weight and metabolic status also affect GLP-1 production

Here are the most common, listed in order of how often they occur: Nausea Diarrhea Vomiting Constipation Abdominal pain Headache Fatigue Acid reflux The reason so many are gastrointestinal in nature is because GLP-1 weight-loss medications like Wegovy slow down the speed at which food moves through your GI tract

type 2 diabetes Source: Bank of America 16

Incretin therapies like GLP-1s were created as glucose-lowering medications specifically to help people with diabetes