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Researchers who treat KPV as a replacement for corticosteroids or biologics without understanding its narrow mechanistic niche consistently report disappointmentnot because the peptide failed, but because the application was mismatched
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Studies have observed decreased cyclooxygenase-2 (COX-2) gene expression, reduced myeloperoxidase activity, and lower levels of pro-inflammatory cytokines including interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-)
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