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References Dakshinamurti S, Dakshinamurti K

ACC guidelines published in 2024 for lower extremity arterial disease management do not discuss GLP-1 RA as part of management, likely due to the recency of the STRIDE trial findings [45]

Elevated levels of O 2 , H 2 O 2 , OH , nitric oxide (NO), and glutathione disulfide (GSSG), peroxides, depletion of GSH, and oxidation of methionine and cysteine moieties in cataractous lenses, all indicate the involvement of ROS and RNS in cataract formation [5965]

[1] [15] While specific fatigue rates are not prominently highlighted in the FDA-approved labeling, post-marketing surveillance and patient-reported experiences suggest that some individuals do experience tiredness, particularly during the first 48 weeks of treatment or following dose increases