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[Abstract]2022 Aug 8;7(15):e160247
When researchers block histaminergic neurons in animals, it causes sleep-wake cycle fragmentation and increased delta power in non-REM sleep.[ref] Mast cells release histamine: Most people are familiar with histamine from its role in allergic reactions causing a runny nose, itching, hives, etc
Studies in GHD patients receiving hGH therapy report [15]: Improved quality of life 2-5% increase in lean muscle mass 7-10% lower fat mass and a -1.2inch mean decrease in waist circumference 11-16% lower LDL (bad) cholesterol Yet, the benefits of hGH therapy in otherwise healthy individuals appear to be more modest
26864-1-AP
19 These transaminase elevations did not amount to any clinical significance, and after the APAP was discontinued the transaminase levels returned to normal
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