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Endothelial cells play a fundamental role in chronic oxidative stress and the development of atherosclerosis, thrombosis and lung injury, principal complications of SARS-CoV-2-mediated tissue and organ dysfunction (Chang et al., 2021)

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The treated mice were administered with T1 at dose levels of 1500, 3000 and 6000 mg/kg and the control mice were administered with vehicle control (4% Tween 80 in water for injection (Brand: SIGMA, Lot No.: 44H01211) was used for vehicle control and dosing solution preparation)

The recommended glutathione IV treatment schedule typically involves one to three sessions per week during an initial loading phase, followed by less frequent maintenance visits