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Under homeostatic conditions, transient activation of NRF2 is cytoprotective, allowing for adaptation to various cell intrinsic (i.e., reactive oxygen species (ROS) generated by mitochondrial function) and extrinsic (i.e., xenobiotic) stressors (Kensler et al, 2007
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Nanoemulsions for delivery of anticancer drug: a novel approach
Furthermore, since GSH causes a switch from eumelanin to phaeomelanin, it may increase UV photosensitivity, DNA damage and skin cancers in previously protected populations
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