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Across analyses, a recurring contrast is observed between (i) a reproductive subtypeoften reported as higher LH and SHBG with elevated androgens despite comparatively lower BMI and fasting insulinand (ii) a metabolic subtype, characterized by higher adiposity with higher glucose/insulin measures and lower SHBG (and, in some reports, lower LH) (51)

"If you are taking medication to lower your sugar levels, it is advisable to avoid excess sugar consumption," Dr

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Adherence is another major issue one study suggested that roughly two-thirds of patients discontinue GLP-1 therapy within the first year, often due to high costs, gastrointestinal side effects, lack of perceived benefit, or difficulty maintaining lifestyle changes