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346 In parallel, modulation of microbial metabolites offers therapeutic leverage: promoting beneficial compounds such as 3-IAA, which enhances ROS and chemosensitivity, or suppressing lactate-secreting strains such as Lactobacillus iners may reverse resistance-associated metabolic reprogramming

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Genetic variants inform baseline receptor sensitivity and metabolic potential, but they do not predict whether GLP-1 will trigger or worsen autoimmune activity

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At the appointment, here are some questions you might like to ask your provider: What dosing stage am I at and when am I likely to see results

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