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And semaglutide, a drug approved for chronic weight management and type 2 diabetes, delivered robust therapeutic effects across both conditions simultaneously

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This was achieved by demethylating the promoters of 14-3-3, CHK2 and DAPK-1 genes, promoting the expression of these genes, and then activating the G2/M checkpoint response in osteosarcoma cells, to improve the radiotherapy effect of osteosarcoma 10 (Figure 1 and Table 1)

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