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Experimental studies in animals provide additional insight: GLP-1 analogs increased testosterone synthesis and improved sperm mitochondrial integrity in diabetic and obese models

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Neural circuits driven by GLP-1 and GLP-1R in the NTS and hypothalamus has been shown to contribute to many aspects of energy balance control 4,6

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The look is usually a mix of collagen loss, water loss from the barrier, and subtle laxity that shows in certain lighting