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(PubMed) Lu J, Holmgren A
Leuco-methylthioninium bis (hydromethanesulfonate) is one such compound that has been reported to prevent tau aggregation and has subsequently been tested in cell lines and a transgenic mouse model of PD with encouraging results (Schwab et al
Keep in the original light-protective container and do not freeze
Keep the vial wrapped in aluminum foil to protect from light exposure, which accelerates degradation
in diabetic rodents, Fan and colleagues [77] demonstrated that intravitreal exedin-4 injection reduced retinal cell loss, maintained Bcl-2/Bax ratios, whose imbalance is associated with retinal cell apoptosis, prevented activation of pro-apoptotic AKT, and prevented excess reactive gliosis
